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The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

Using two separate drugs to lose weight naturally can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err along the side of caution and allow FDA do its job and demand some investigation be done so that the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on their medications.

Researchers discovered that participants investing in this drug for the year, dropped a few pounds within four weeks and have kept the body weight off through the 56 weeks of the study. Contrave is often a combination in the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs that are made up of multiple active ingredient, which may make them far better and safer.

Combo-pilling may be the newest fad or also the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that since right now there aren't any long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure level and pulse rate, and must not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must not be used in patients with uncontrolled high blood pressure, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients for the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.


From a psychiatric viewpoint, evidence suggests that the ordinary neural mechanism for goal-directed behavior has been hijacked by the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus along with the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).
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